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Jan 24, 2024
Young, Sarah; Heller, Anna-Dorothea; Garske, Daniela; Rummler, Maximilian; Qian, Victoria; Ellinghaus, Agnes; Duda, Georg; Willie, Bettina; Grüneboom, Anika; Cipitria, Dr. Amaia, 2024, "From breast cancer cell homing to the onset of early bone metastasis: the role of bone (re)modeling in early lesion formation", https://doi.org/10.17617/3.5QKDMH, Edmond, V1
Breast cancer often metastasizes to bone causing osteolytic lesions. Structural and biophysical changes are rarely studied, yet are hypothesized to influence metastatic progression. Here, we developed a mouse model of early bone metastasis and multimodal 3D imaging to quantify cancer cell homing, dynamic bone (re)modeling and onset of bone metastas...
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